Technical Information by Application
Pharmaceutical Applications
Polyvinyl alcohol is listed on the specifications of pharmaceutical excipients and used not only in Japan, but in the US, Europe, and other countries as well.
Our GOHSENOL™ EG complies with the excipient specifications of JPE, USP, as well as EP.
■Specialty Grades：High Purity PVOH EG Series
- Features
- The refining process of GOHSENOL™ EG removes impurities to the utmost.
Our production facilities, manufacturing process, and quality system are managed in compliance with our self-imposed standards of GMP.
- Applications
-
- ・Granulation binder
- ・Binding agent
- ・Coating
- ・Thickener (eye-drop)
- ・Gel Patch (cataplasm)
- ・Emulsifier
- ・Drug delivery film Substrate
- Physical Property data
| Properties | Polyvinyl Alcohol (PVA)*1 |
Hydroxypropyl Cellulose (HPC) |
Hydroxypropyl Methyl Cellulose (HPMC) |
|---|---|---|---|
| Viscosity*2 (mPa・s) |
4.9 | 49.0 | 11.1 |
| Tensile strength (MPa) |
119.4 | 5.1 | 46.9 |
| Linear expansion (%) |
188.4 | 103.4 | 102.7 |
| Young modulus (MPa) |
672 | 419 | 2,251 |
*1. Polyvinyl Alcohol : GOHSENOL™ EG-05PW
*2. 4% aqueous solution
| Properties | Permeation rate of O2 gas*2 (cc/m2･day･atm) |
Permeation rate of water vapor*3 (g/m2･day･atm) |
||
|---|---|---|---|---|
| 25℃ 60%RH | 40℃ 75%RH | 25℃ 60%RH | 40℃ 75%RH | |
| PVA*1 | 0.74 | 18 | 3 | 85 |
| HPC | 128 | >200 | 95 | 470 |
| HPMC | 152 | >200 | 186 | 740 |
*1. Grades ： GOHSENOLTM EG-05PW
Film thickness ： 100μm (made by method of Pool cast）
*2Measuring machine of permeation of the O2 gas ： OXTRAN2/20
*3. The method of permeation of water vapor ： Comply with JIS Z 0208
- Inquiry about EG series (Pharmaceutical Excipient Grades)
- Acetyl and Fine Chemicals Dept. Basic Products Segment
TEL: +81-3-6436-2813 / FAX: +81-3-6436-2820
